Study reveals biological mechanism to explain why respiratory viruses increase in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights viruses responsible for upper respiratory tract infections. Further testing revealed that this protective response is inhibited in colder temperatures, making infection more likely to occur. The new study, published December 6 in The Journal …

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Researchers explore the correlation between the dynamic pattern of SARS-CoV-2 clearance and viral load

In a recent article published in Nature Reviews Microbiologythe researchers sought to establish an association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load, indicating its ribonucleic acid (RNA) levels, and the presence of infectious virions. Study: SARS-CoV-2 viral load and clearance kinetics. Image Credit: CROCODILE/Shutterstock In addition, they examined the host and other …

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The real reasons why your family is sick right now | Health

Something is disrupting the normal seasonal streams of cold and flu viruses. They were down to a trickle during the early part of the Covid pandemic only to burst through human populations this year. Some public health experts have called it “tripledemia,” but it could even be described as quadrupledemia. In the northern hemisphere, the …

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Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic disease, causing one in seven babies born to infected mothers to suffer neurodevelopmental deficiencies. A new study published in the journal Cell shows that some mothers avoid hurting their babies because they develop a very strong neutralizing antibody. This demonstrates the importance of such antibodies in protecting …

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Hemagglutinin stem immunogens may hold the key to broad protection against influenza A viruses

In a recent article published in Immunitythe researchers proposed that vaccines targeting the immunosubdominant but conserved haemagglutinin (HA) stem could elicit broadly neutralizing antibodies (bnAbs) against influenza A viruses. Study: Coimmunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses. Image Credit: Pink Eyes/Shutterstock Background Influenza viruses are highly …

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The effect of vaccination-induced immunity on viral loads of the Omicron variant of SARS-CoV-2

In a recent study published in nature communicationsThe researchers analyzed nationwide vaccination data and cycle threshold value data from four laboratories in Israel that perform quantitative reverse transcription-polymerase chain reaction (qRT-PCR) testing of severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2) to determine the effect of vaccination. induced immunity on viral loads of the SARS-CoV-2 …

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A review of respiratory syncytial virus vaccines

Respiratory syncytial virus (RSV) causes respiratory diseases such as pneumonia and bronchiolitis, mainly affecting children under five years of age and the elderly over 65 years of age. Study: Preliminary data on messenger RNA (mRNA) vaccines against respiratory syncytial virusPreliminary data on messenger RNA (mRNA) vaccines against respiratory syncytial virus. Image credit: ART-ur/Shutterstock The results …

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SpyCatcher-SpyTag technology used to develop a recombinant protein-based intranasal vaccine against SARS-CoV-2

The results of a new study published in the bioRxiv* The preprint server showed that the SpyCage intranasal vaccine platform can protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and may prove to be a versatile and adaptable modality for formulation of intranasal vaccines targeting respiratory pathogens. Study: Intranasal vaccine that mimics virus particles …

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Ancient viral DNA in human genomes protects human cells against certain current viruses

Viral DNA in human genomes, embedded there from ancient infections, serves as an antiviral that protects human cells against certain current viruses, according to new research. The article, “Evolution and antiviral activity of a human protein of retroviral origin,” published October 28 in Sciencesprovides proof of principle for this effect. Previous studies have shown that …

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