Ohio State vs. Odds Notre Dame Distribution: 2022 College Football Picks, Week 1 Predictions by Model on a 45-32 Run

College football stages its first big, can’t-miss matchup of the 2022 season when the No. 2 Ohio State Buckeyes and No. 5 Notre Dame Fighting Irish collide in the teams’ season opener Saturday at Ohio Stadium in Columbus. The Buckeyes are coming off a season in which they failed to win the Big Ten title for the first time since 2016. They finished the season with a win over Utah in the Rose Bowl. Meanwhile, the Fighting Irish are playing their first game under new head coach Marcus Freeman. He replaces Brian Kelly who left for LSU.

Kickoff is at 7:30 pm ET. The Buckeyes are 17-point favorites in the latest Ohio State vs. Notre Dame from Caesars Sportsbook, while the over/under of total points scored is 59. Before choosing Notre Dame vs. Ohio State, be sure to check out the university. Soccer predictions and betting tips from SportsLine’s proven computer model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated an impressive profit of nearly $3600 for $100 players on their top-rated college football picks against the spread. He enters Week 1 of the 2022 college football season riding a 45-32 streak in all of the top-rated college football money line and spread picks going back to 2021. Anyone who has followed him has seen large profits.

Now, the model has set her sights on Ohio State vs. Notre Dame and simply posted their CFB picks and predictions. You can head over to SportsLine now to check out the model picks. Here are various college football odds and betting lines for Notre Dame vs. Ohio State:

  • Difference between Ohio State and Notre Dame: Buckeyes -17
  • Ohio State vs. Notre Dame Over/Under: 59 points
  • Ohio State Money Line Vs. Notre Dame: Buckeyes -800, Fighting Irish +550
  • OHST: CJ Stroud finished second in the country in passer efficiency rating (186.6) last year.
  • ND: The Irishman led the nation in fumble recoveries (19) last season.
  • Ohio State vs. Picks Notre Dame: Check out the picks on SportsLine

Why Ohio State can cover

Ohio State has arguably the best college football player in Stroud. Stroud, a sophomore from Inland Empire, Calif., is coming off a season in which he set 17 program records and finished second in the country in passer efficiency rating (186.6). For his efforts, he was named the Big Ten Offensive Player of the Year and finished fourth in the Heisman Trophy voting.

Also, the Buckeyes have recently excelled against ranked teams. Over the past 10 seasons, Ohio State is 36-9 against ranked opponents. The team is also 14-3 against the top 25 foes at home during that time.

Why Notre Dame can cover

Notre Dame has an elite pass-rusher in Isaiah Foskey. A 6-foot-5 junior from Antioch, Calif., Foskey led the team last season with 11 sacks, the third-most in a single season in program history. With a similar season in 2022, he can top the show’s all-time sack record (24.5), set by Justin Tuck (2002-04).

With Foskey applying pressure, the defense excelled at forcing turnovers last season. The Irish led the nation in fumble recoveries with 19 (Foskey forced six of them), helping them rank fourth in the country in turnover margin (+1.31 turnovers per game).

How to make predictions between Notre Dame and Ohio State

SportsLine’s model leans on the total, projecting a combined 60 points. The model also says that one side of the differential hits in more than 60% of the simulations. You can only see the model choice on SportsLine.

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So who wins Ohio State vs. Notre-Dame? And which side of the difference affects more than 60% of the simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed your college football picks, and find out.

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