College Football Picks, Schedule: Anti-Spread Predictions, Odds For Key Week 1 Games On Friday

The action for Week 1 of the 2022 college football season continues Friday night with eight more games to whet your appetite before the full slate of Saturday’s contests begins. While the second of five straight days of college football has few teams ranked (only No. 15 Michigan State is represented in the preseason AP Top 25), it still has a lot to go on story-wise across the country. .

Teams from four of the five Power Five conferences will be in action, though only Big Ten interdivisional rivals Illinois and Indiana will meet in conference play. All told, there’s enough football to fill two, three, or even four screens given the loaded 7pm kickoff slate. Night owls can enjoy coverage that will extend past midnight with TCU and Colorado playing into the early hours of Saturday morning.

Be sure to stick with CBS Sports throughout the night for college football coverage from kickoff onward. Let’s take a look at our expert picks for the best games on Friday of week 1.

Odds via Caesars Sportsbook | All Eastern Times

featured game | Michigan State Spartans vs. West Michigan Broncos

19:00 | ESPN, fuboTV (Free Trial) — Michigan State was an entertaining team to watch last season because they had an explosive offense with a tremendous playmaker in Kenneth Walker, and combined it with a secondary that couldn’t cover anyone. Walker is gone, but the offense should still be able to move the ball against the Broncos, and most of that secondary remains intact. There are also new transfers on the defensive side of the ball, and there could be some issues as that unit solidifies in the first game of the season. Sparty could get 45 on its own. Selection: more than 54.5 –Tom Fornelli

19:00 | ESPNU, fuboTV (Free Trial) — After winning its last five regular season games last year to qualify for a bowl game, Old Dominion brings back ample early experience for Year 3 of the Ricky Rahne era. Virginia Tech is playing its first game under new coach Brent Pry, and this doesn’t look like an instant rebuild. Considering the Monarchs lost by just 14 on the road to the Hokies in 2019 during a 1-11 season, they seem like a safe bet to keep this one close to home all the way now that the program is on a much stronger footing. Collect: Ancient Domain +6.5 –David Cobb

Illinois vs. Indiana

featured game | Indiana Hoosiers vs. Illinois Fighting Illini

20:00 | FS1, fuboTV (Free Trial) — Each team has an advantage that they are looking to exploit in this game. Indiana has not announced its starting QB and has new coordinators. This means that Illinois has not been able to prepare for this game with any certainty of what it will see. Also, Illinois played on Saturday of last week and had to prepare a game plan for Wyoming before turning around in a short week to play a road game against the Hoosiers. Meanwhile, Indiana has been able to prepare for Illinois all offseason and now has a movie of the game to dissect. Of course, what Illinois has going for it is that it has a game under its belt. It will be interesting to see how that affects the game. I don’t have a great read on how this one will go, but my gut tells me that neither team outperforms the other, so taking the points with Illini is the more attractive option. Prediction: Illinois +3 –Tom Fornelli

TCU vs. Colorado

22:00 | ESPN, fuboTV (Free Trial) — The Horned Frogs enter a new era under coach Sonny Dykes, but don’t expect too many bumps in their debut. Colorado lost seven games by two or more touchdowns in 2021, and likely has no answers for what should be a dynamic passing game headed by potential first-round receiver Quentin Johnston. TCU will play it safe and use their talents to pull off a landslide victory. Pickup: TCU-8 — Shehan Jeyaraja

Which college football picks can you confidently make in Week 1 and which heavy favorite will go down hard? Visit SportsLine to see which teams will win and cover the spread, all from a proven computer model that has generated nearly $3,600 in profits over the last six seasons and find out.

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