2022 Week 1 College Football Odds, Picks & Predictions – Proven Computer Model Backing Florida, Alabama

After a limited Week 0 roster, Week 1 of the college football schedule begins Thursday night. There are dozens of games taking place over Labor Day weekend. There are games on Thursday, Friday and Saturday, followed by a separate showdown on Sunday and Monday night. LSU is listed at -3 against Florida State in Caesars Sportsbook’s Week 1 college football odds for Sunday’s game, while Clemson is at -21.5 against Georgia Tech on Monday.

Considering Week 1 college football lines of all sizes, where are the best values ​​in college football spreads? And which favorites might be in for a surprise? Before you lock in any college football picks for Week 1 of the 2022 season, be sure to check out the latest college football predictions from SportsLine’s tested model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated an impressive profit of nearly $3,600 for $100 players on their top-rated college football picks against the spread. He enters Week 1 of the 2022 college football season riding a 45-32 streak in all of the top-rated college football spread and money line picks going back to 2021. Anyone who has followed him has seen large profits.

Now, he’s turned his attention to the latest college football odds for Week 1 from Caesars and has locked down picks for every FBS matchup. Head here to see each choice.

Best College Football Predictions for Week 1

One of the college picks the model is high on for Week 1: Florida (+3) easily stays within home-court advantage against No. 7 Utah at 7 pm ET. The Gators will ride the arm and legs of quarterback Anthony Richardson, who is projected to throw for nearly 300 yards and rush for more than 40 yards. Outside of Richardson, Florida also has a stable of running backs who can rack up rushing yards and that group is expected to rush for more than 100 yards on their own.

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Utah went 10-4 last season and finished 12th in the final AP poll, but the Utes struggled when they ventured out of the Pac-12. They lost all three of their non-conference FBS games, all of which were not at home and two of which were against unranked squads. The defense allowed 35.7 PPG in those three games, a huge jump from the 19.2 points it allowed while beating the Pac-12. That defense is expected to get worse after Utah lost Pac-12 Defensive Player of the Year LB Devin Lloyd to the NFL.

Florida went 3-1 in non-conference FBS games last year and has home-court advantage on Saturday. The Gators are expected to win outright and thus cover almost 60% of the simulations.

Another prediction: No. 1 Alabama (-41.5) has no problem handling the huge difference against Utah State in a matchup at 7:30 pm ET in Tuscaloosa on Saturday. Alabama is used to huge lines, but the Tide continues to cover regularly, going 24-17 against the sidelines since 2019. That 58.5% coverage rate is 22nd best in college football during that span.

Utah State is no stranger to winning in recent years, but the Aggies weren’t very impressive in their Week 0 start, outscoring UConn by just 11 points at home. Alabama is again loaded on both sides of the ball and will be looking to make a statement in Week 1 after coming up short in last year’s title game. The SportsLine model projects that Alabama quarterback Bryce Young throws for more than 350 yards as Tide coverage in nearly 60% of the simulations. His scoring spree also helps the Over clear over 60% of the time. See what other outfits the model likes here.

How to make college football picks for week 1

The model has also made the call on who wins and covers in all other FBS matchups in Week 1, and is calling out a heavy favorite to go down hard in a shocking upset. She can only get each pick for each game on SportsLine.

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So what college football picks can you make with confidence? And which big favorite goes down hard? Check out the latest college football odds below, then visit SportsLine to see which teams are winning and making up the spread, all from a proven computer model that has generated nearly $3,600 in profits over the past six seasons and find out.

College football odds for Week 1 (via Caesars)

See the full Week 1 college football picks, odds and predictions here

Thursday, September 1

Ball State at Tennessee (-35, 68)

West Virginia at Pittsburgh (-7.5, 52)

featured game | Pittsburgh Panthers vs. West Virginia Mountaineers

Penn State at Purdue (+3.5, 53.5)

featured game | Purdue Boilermakers vs. Penn State Nittany Lions

Friday, September 2

Illinois at Indiana (-3, 45.5)

featured game | Indiana Hoosiers vs. Illinois Fighting Illini

TCUs at Colorado (+13.5, 55.5)

featured game | Colorado Buffaloes vs. TCU Horned Frogs

Saturday, September 3

Colorado State at Michigan (-27.5, 58.5)

featured game | Michigan Wolverines vs. Colorado State Rams

Cincinnati at Arkansas (-6, 51.5)

featured game | Arkansas Razorbacks vs. Cincinnati Bearcats

Oregon at Georgia (-17.5, 52)

featured game | Georgia Bulldogs vs. Oregon Ducks

UTEP at Oklahoma (-31.5, 57)

Rice at USC (-33.5, 61.5)

Utah at Florida (+3, 51)

featured game | Florida Gators vs. Utah Utes

Utah State at Alabama (-41.5, 62.5)

Notre Dame at Ohio State (-17.5, 58.5)

featured game | Ohio State Buckeyes vs. Notre Dame Fighting Irish

Sunday, September 4

Florida State at LSU (-3, 51.5)

featured game | LSU Tigers vs. Florida State Seminoles

Monday, September 5

Clemson at Georgia Tech (+21.5, 49)

featured game | Georgia Tech Yellow Jackets vs. Clemson Tigers

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